![]() By 8 hr post amputation, Wnt signaling became restricted to oral regeneration. We found that the initial response to amputation at both wound sites is identical and includes widespread apoptosis and the activation of the oral-specifying Wnt signaling pathway. To understand the transcriptional regulation underlying this adaptive response, we characterized transcript abundance and chromatin accessibility during oral and aboral regeneration in the cnidarian Hydra vulgaris. ![]() During whole-body regeneration, a bisection injury can trigger two different types of regeneration. ![]()
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